Weill Cornell Medicine Events

“Translating Thought into Blood Flow in the Brain: Capillaries as Sensors of Neural Activity”

We have recently shown that brain capillaries act as a neural activity-sensing network by initiating and transmitting an electrical signal, mediated by potassium channel activation that propagates through the interconnected endothelial cells comprising the capillaries that line all blood vessels. This concept explains the rapid and coordinated delivery of blood to active neurons. Using a mouse model of a monogenic form of Singular Value Decomposition (SVD), we have discovered early defects that result in a loss of this electrical signaling mechanism and impaired delivery of blood to active neurons - defects that involve changes in extracellular matrix composition.

Mark T. Nelson, Ph.D.,
Pharmacology Chair and Professor
University of Vermont Larner College of Medicine

Thursday, November 14 at 4:00pm to 5:00pm

Weill Auditorium
1300 York Ave New York, NY 10065

Event Type

Lecture/Seminar

Departments

Brain and Mind Research Institute

Mission

Research

Photo Alt Text

brain

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