"Updates in Blood-Based and Neuroimaging Biomarkers of Acute Traumatic Brain Injury"

John K. Yue, M.D.
Resident Physician (PGY-5)
Department of Neurological Surgery
University of California, San Francisco

45-minute seminar followed by 15-minute discussion. All are welcome to attend!

Abstract: Traumatic brain injury remains a major cause of morbidity and mortality worldwide. Due to its heterogeneity in clinical presentation and radiographic injury, TBI diagnosis and management have been hampered by imprecise approaches to injury classification. Over the past decade, significant improvements have been made in blood-based (GFAP, UCH-L1) and neuroimaging (CT, MRI, DTI) biomarkers to aid in TBI diagnosis and prognostication, in accordance to the data standards outlined by the National Institutes of Health TBI Common Data Elements. The relationship between priority biomarkers and risk factors for injury and outcome will be reviewed.

Bio: Dr. John Yue received his M.D. from University of California San Francisco and is a senior resident in the UCSF Department of Neurosurgery. His clinical interests include neurotrauma, neurocritical care, multimodal neuromonitoring, blood-based and neuroimaging biomarkers, longitudinal outcomes, and predictive modeling. Dr. Yue was awarded the American Association of Neurological Surgeons Neurosurgery Research and Education Foundation Fellowship in Neurotrauma (2022-23) and the Congress of Neurological Surgeons Natus Resident Award in Traumatic Brain Injury (2021). He has given over 20 podium sessions across annual national conferences in neurosurgery and neurotrauma. Dr. Yue has co-authored 160 peer-reviewed publications and 6 textbook chapters across 13 years of focused research efforts in neurotrauma. He currently serves on the Editorial Board for several trauma and brain injury journals. 

This seminar series aims to create and sustain collaborations between researchers at Weill Cornell Medicine who have research interests in brain injury. To join the Listserv please send an email to sut2006@med.cornell.edu.

Sudhin A. Shah, Ph.D.
Assistant Professor of Neuroscience in Radiology
Brain Health Imaging Institute
Weill Cornell Medicine
sut2006@med.cornell.edu

Tracy Butler, M.D.
Associate Professor of Neurology in Radiology
Brain Health Imaging Institute
Weill Cornell Medicine
tab2006@med.cornell.edu