Food, travel, and accommodations provided.

Wednesday, March 22

Bus departure from Ithaca: 7:00 a.m.
(arrival in NYC about 11 a.m.)

Lunch: 11:30 am

Welcome and Introductions: 12:15 p.m.

Session 1: Back to basics — Understanding the ‘M’ of AMR: 12:30 – 2:30 p.m.      

"The lipid II cycle as a target for antibiotics"
John Helmann, Professor, Department of Microbiology, College of Agriculture and Life Sciences

"Outer membrane modifications promote high-level beta lactam tolerance in Gram-negative pathogens"
Tobias Dörr, Associate Professor, Department of Microbiology, College of Agriculture and Life Sciences

"Ribosome physiology"
Heather Feaga, Assistant Professor, Department of Microbiology, College of Agriculture and Life Sciences

"Physiologic mediators of intrinsic antibiotic resistance"
Sabine Ehrt, Professor, Department of Microbiology & Immunology, Weill Cornell Medicine

Session 1 Keynote: 2:30 - 3:30 p.m.

"Optogenetic feedback control of gene expression and antibiotic resistance in single cells"
Mary Dunlop, Associate Professor, College of Engineering, Boston University

Poster Session with Refreshments, Griffis Faculty Club, 4:30 – 6:00 p.m.
(beer/wine and light snacks)

Dinner at The Alvin Public House, 406 E 64th St: 6:30 p.m.

Thursday, March 23 

Breakfast: 7:30 a.m.  

Session 2 Keynote: 8:30 – 9:30 a.m.

Yonatan Grad, Melvin J. and Geraldine L. Glimcher Associate Professor of Immunology and Infectious Diseases, Department of Immunology and Infectious Diseases, T.H. Chan School of Public Health, Harvard University

Session 2: Taking stock and sizing up the OneHealth ecology of AMR: 9:30 – 12:00 p.m.                                   

"Antimicrobial resistance detection in clinical microbiology"
Lars Westblade, Associate Professor, Pathology and Laboratory Medicine and Department of Medicine, Division of Infectious Diseases; Director of Clinical Microbiology, New York-Presbyterian Hospital- Weill Cornell Medicine

"Antimicrobial resistance in foodborne pathogens: Salmonella and beyond"
Martin Wiedmann, Gellert Family Professor, Department of Food Science, College of Agriculture and Life Sciences

"Antimicrobial resistance in the microbiome"
Ilana Brito, Associate Professor, Mong Family Sesquicentennial Faculty Fellow in Biomedical Engineering, Meinig School of Biomedical Engineering

"Antimicrobial use in animal agriculture through a One Health lens – How much is used and can we use less?"
Renata Ivanek, Associate Professor, Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine

"Insight from the social and behavioral sciences on AMR: Communication, context and motivation"
Amelia Greiner Safi, Associate Professor of Practice, Department of Public and Ecosystem Health, College of Veterinary Medicine

Lunch with Working Groups: 12:00 – 1:00 p.m.

WG1 Collaborative Opportunities for Novel Therapy Development
Goals:

• Identify clinical problems (“data gaps”) of tolerance and resistance that need to be addressed

• Create collaborations between applied/clinical scientists and basic scientists to develop integrated translational program projects.

• Create new antibiotics based upon novel targets

• Develop alternatives to antibiotics that target the pathogen or the host response

WG2 Collaborative Opportunities in Pathology, Pharmacy and the Clinical Environment
Goals:

• Develop new means to track resistant organisms and their resistance genes

• Provide rapid and accurate susceptibility tests to aid clinical decisions

WG3 Epidemiology/Public Health/Stewardship
Goals:

• Monitor antimicrobial resistance in pathogens of medical and veterinary importance

• Develop public health strategies to prevent the emergence of antimicrobial resistance based upon these data

• Identify antimicrobial stewardship practices that ensure enhanced clinical outcomes in animal and human populations

Session 3: Taking the ‘R’ out of AMR: Innovative approaches to targeting resistant pathogens: 1:00 – 3:30 p.m.                         

"Novel approaches to targeting animal to human transmission of foodborne pathogens"
Craig Altier, Professor of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine

"Scalable fluidic tools for addressing antimicrobial resistance"
Nate Cira, Assistant Professor, Meinig School of Biomedical Engineering

"Transmission blocking strategies against antimicrobial resistance"
Kyu Rhee, Professor of Medicine, Weill Cornell Medical College

"Fluid dynamics-based approaches to microbial infection and decontamination"
Sunny Jung, Professor, Department of Biological and Environmental Engineering, College of Agriculture and Life Sciences

"CRISPR interference and riboswitch-based approaches to antimicrobial resistance              
Ailong Ke, Robert J. Appel Professor, Department of Molecular Biology and Genetics, College of Agriculture and Life Sciences

Session 3 Keynote: 3:30 – 4:30 p.m.

Carl Nathan, R.A. Rees Pritchett Professor of Microbiology, Weill Cornell Medicine

Summary and Concluding Remarks: 4:30 p.m.

Meeting adjourned: 4:45 p.m.

Bus departure for Ithaca: 5:00 p.m.
Boxed meals for traveling guests